Endometrial Biopsy Sugar Land, TX

Frequent Asked Topics

What is an endometrial biopsy?

An endometrial biopsy is a procedure in which a tissue sample is obtained from the endometrium (the inside lining of the uterus) and is then observed under a microscope. The tissue is thoroughly examined for any cell abnormalities or cancer. The test also helps determine the cause of abnormal menstrual periods and can be used to screen for endometrial cancer. 

How the Test is Performed

  • The cervix is cleaned with an antiseptic solution. 
  • The cervix may then be gently grasped with an instrument to hold the uterus steady. Another instrument may be needed to gently stretch the cervical opening if there is tightness.
  • An endometrial catheter is gently passed through the cervix into the uterus to collect the tissue sample.
  • The tissue sample and instruments are removed.  The tissue is sent to lab where it is examined under the microscope
  • The procedure can be done without anesthesia

How to Prepare for the Test

Before the test:

  • Tell your doctor about all the medicines you take. These include blood thinners such as warfarin, clopidogrel, and aspirin.
  • You may be asked to have a test to make sure you are not pregnant.
  • In the 2 days before the procedure, do not use creams or other medicines in the vagina.
  • You can take pain medicine, such as ibuprofen or acetaminophen one hour before the procedure.

Why the Test is Performed

The test is done to find the cause of:

  • Abnormal menstrual periods (heavy, prolonged, or irregular bleeding)
  • Bleeding after menopause
  • Bleeding from taking hormone therapy medicines
  • Thickened uterine lining seen on ultrasound
  • To determine if you have Endometrial cancer or precancer 

What Abnormal Results Mean

Abnormal uterine bleeding may be caused by:

  • Uterine fibroids
  • Fingerlike growths in the uterus (uterine polyps)
  • Infection
  • Hormone imbalance
  • Endometrial cancer or precancer (hyperplasia)
  • Abnormal bleeding if a woman is taking the breast cancer medicine tamoxifen
  • Abnormal bleeding due to changes in hormone levels (anovulatory bleeding)


Risks for endometrial biopsy include:

  • Infection
  • Slight spotting and mild cramping for a few days
  • Causing a hole in (perforating) the uterus or tearing the cervix (rarely occurs)


Learn about Endometrial Biopsy and its impact on women’s health. Contact us at Sugar Land Advanced OB/GYN Center at (281) 322-2222 to explore treatment options and find relief from chronic pain.